ceesdekker.net - An Overview
ceesdekker.net - An Overview
Blog Article
Nanotechnology gives A selection of alternatives to contribute to biology. Right here I'll current examples the place nanofabrication – the opportunity to make confined buildings with Proportions at will – is made use of to examine the biophysics of single molecules and cells. I will present some illustrations from our lab:
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
Like a individual, I contain the biblical assignment to discover and use almost everything in creation for the benefit of my neighbour. I tend not to working experience any conflict between faith and science. On the contrary, my faith stimulates me to try and do science, to generally be open-minded on earth.’
I am able to barely think about how I, for a geneticist, would be capable to understand basic physics, let alone contend at the best. How did you go over it?
We establish place-of-care diagnostics test of neglected tropical diseases in just source-constrained settings, based on Crspr/Cas9 detecting of pathogen’s DNA in overall body fluids.
The coiled-coil of your human Rad50 DNA mend protein consists of specific segments of greater versatility
MATLAB codes for info processing are available at . Julia codes employed for numerical simulation can be found at .
Atomic pressure microscopy shows that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue
‘Of course, I comprehend persons had been amazed at the time. At the end of the nineties, After i was ceesdekker.net in my forties, I was Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t master Significantly anymore. The sphere went a lot more into the applying side, how you may combine nanotubes into Digital circuits.
Resolving the move measurement in condensin-driven DNA loop extrusion identifies ATP binding given that the action-making course of action
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Many new phenomena ended up identified, and he and his research team set up a number one place During this discipline of study. Dekker and his exploration group found out new physics of nanotubes along with explored the feasibility of molecular electronics. In 1998, they were the primary to build a transistor based upon just one nanotube molecule.
Such as, we think about the nucleopore intricate, a gateway among the mobile nucleus plus the cytoplasm. This is an extremely complex system and as a consequence challenging to research in a mobile, so we use biomimetics. We reconstruct holes after which insert person features on the nucleopore complicated to check transport through it at The only-molecule level.’
It absolutely was a really appealing time, during which I acquired loads of assistance from Delft University of Know-how, exactly where I used to be a professor at enough time, And that i started numerous collaborations with molecular biologists. That aided me study a lot.’